Neutrophil gelatinase-associated lipocalin: a promising biomarker for human acute kidney injury
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چکیده
منابع مشابه
Neutrophil gelatinase-associated lipocalin: a promising biomarker for detecting cardiac surgery-associated acute kidney injury.
Acute kidney injury is a common and significant problem that occurs in a wide variety of clinical settings. Cardiac surgery-associated acute kidney injury continues to be a well-recognized complication of cardiac surgery with associated morbidity and mortality. A lack of early biomarkers for acute kidney injury has prevented timely interventions to mitigate the effects of acute kidney injury. B...
متن کاملCorrection: Urine neutrophil gelatinase-associated lipocalin (NGAL) as a biomarker for acute canine kidney injury
After the publication of this work [1], we became aware of the fact that the values of NGAL reported in this study were concentrations of diluted clinic samples; and therefore for the actual concentration of urine NGAL, the value should multiply the dilution factor. With exception of Figure three (Figure 1 here), all the values of urine NGAL described in this study were detected by in-house ELI...
متن کاملUrine neutrophil gelatinase-associated lipocalin (NGAL) as a biomarker for acute canine kidney injury
BACKGROUND Biomarkers for the early prediction of canine acute kidney injury (AKI) are clinically important. Recently, neutrophil gelatinase-associated lipocalin (NGAL) was found to be a sensitive biomarker for the prediction of human AKI at a very early stage and the development of AKI after surgery. However, NGAL has not yet been studied with respect to dog kidney diseases. The application of...
متن کاملNeutrophil Gelatinase-Associated Lipocalin and Contrast-Induced Acute Kidney Injury.
BACKGROUND Neutrophil gelatinase-associated lipocalin (NGAL) is an early marker of acute kidney injury (AKI). METHODS AND RESULTS Urine NGAL and serum NGAL (sNGAL) were assessed at 2, 6, 24, and 48 hours after contrast media (CM) exposure in 458 high-risk patients (development set). Optimal thresholds in predicting contrast-induced AKI (serum creatinine [sCr] increase ≥0.3 mg/dL at 48 hours a...
متن کاملNeutrophil gelatinase-associated lipocalin (NGAL) as a biomarker for acute renal injury after cardiac surgery.
BACKGROUND The scarcity of early biomarkers for acute renal failure has hindered our ability to launch preventive and therapeutic measures for this disorder in a timely manner. We tested the hypothesis that neutrophil gelatinase-associated lipocalin (NGAL) is an early biomarker for ischaemic renal injury after cardiopulmonary bypass. METHODS We studied 71 children undergoing cardiopulmonary b...
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ژورنال
عنوان ژورنال: Biomarkers in Medicine
سال: 2010
ISSN: 1752-0363,1752-0371
DOI: 10.2217/bmm.10.12